5NVN

Crystal structure of the human 4EHP-4E-BP1 complex

5NVN の概要

• エントリーDOI: 10.2210/pdb5nvn/pdb
• 分子名称: Eukaryotic translation initiation factor 4E type 2, Eukaryotic translation initiation factor 4E-binding protein 1, FORMIC ACID, ... (4 entities in total)
• 機能のキーワード: translational regulation, translation initiation, cap-binding protein, eif4e-binding protein 1, translation
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 52946.55

構造登録者

Peter, D.,Sandmeir, F.,Valkov, E. (登録日: 2017-05-04, 公開日: 2017-07-26, 最終更新日: 2024-01-17)

• 主引用文献: Peter, D.,Weber, R.,Sandmeir, F.,Wohlbold, L.,Helms, S.,Bawankar, P.,Valkov, E.,Igreja, C.,Izaurralde, E.; GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.; Genes Dev., 31:1147-1161, 2017; PubMed: 28698298; DOI: 10.1101/gad.299420.117

実験手法

X-RAY DIFFRACTION (1.9 Å)