5NTI
Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds
Summary for 5NTI
Entry DOI | 10.2210/pdb5nti/pdb |
Descriptor | Nuclear receptor ROR-gamma, ASN-SER-HIS-GLN-LYS-VAL-THR-LEU-LEU-GLN-LEU-LEU-LEU-GLY-HIS-LYS-ASN-GLU-GLU-ASN, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, ... (4 entities in total) |
Functional Keywords | nuclear hormone receptor, ligand-binding domain, agonist, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P51449 |
Total number of polymer chains | 8 |
Total formula weight | 130102.59 |
Authors | Kallen, J. (deposition date: 2017-04-28, release date: 2017-06-21, Last modification date: 2024-05-01) |
Primary citation | Kallen, J.,Izaac, A.,Be, C.,Arista, L.,Orain, D.,Kaupmann, K.,Guntermann, C.,Hoegenauer, K.,Hintermann, S. Structural States of ROR gamma t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds. ChemMedChem, 12:1014-1021, 2017 Cited by PubMed: 28590087DOI: 10.1002/cmdc.201700278 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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