5NTI

Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds

Summary for 5NTI

Entry DOI	10.2210/pdb5nti/pdb
Descriptor	Nuclear receptor ROR-gamma, ASN-SER-HIS-GLN-LYS-VAL-THR-LEU-LEU-GLN-LEU-LEU-LEU-GLY-HIS-LYS-ASN-GLU-GLU-ASN, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, ... (4 entities in total)
Functional Keywords	nuclear hormone receptor, ligand-binding domain, agonist, signaling protein
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus : P51449
Total number of polymer chains	8
Total formula weight	130102.59
Authors	Kallen, J. (deposition date: 2017-04-28, release date: 2017-06-21, Last modification date: 2017-07-19)
Primary citation	Kallen, J.,Izaac, A.,Be, C.,Arista, L.,Orain, D.,Kaupmann, K.,Guntermann, C.,Hoegenauer, K.,Hintermann, S. Structural States of ROR gamma t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds. ChemMedChem, 12:1014-1021, 2017 Cited by PubMed: 28590087 DOI: 10.1002/cmdc.201700278 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation