5NT2

Complex of influenza A NS1 with TRIM25 coiled coil domain

Summary for 5NT2

Entry DOI	10.2210/pdb5nt2/pdb
Descriptor	Non-structural protein 1, E3 ubiquitin/ISG15 ligase TRIM25 (2 entities in total)
Functional Keywords	viral protein/host protein/e3 ligase/trim protein, ligase
Biological source	Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) More
Cellular location	Host nucleus : P03496 Cytoplasm : Q14258
Total number of polymer chains	8
Total formula weight	191518.31
Authors	Koliopoulos, M.G.,Rittinger, K. (deposition date: 2017-04-27, release date: 2018-05-23, Last modification date: 2024-01-17)
Primary citation	Koliopoulos, M.G.,Lethier, M.,van der Veen, A.G.,Haubrich, K.,Hennig, J.,Kowalinski, E.,Stevens, R.V.,Martin, S.R.,Reis E Sousa, C.,Cusack, S.,Rittinger, K. Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition. Nat Commun, 9:1820-1820, 2018 Cited by PubMed: 29739942 DOI: 10.1038/s41467-018-04214-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.259 Å)

Structure validation