5NAN

Crystal Structure of human IL-17AF in complex with human IL-17RA

Summary for 5NAN

Entry DOI	10.2210/pdb5nan/pdb
Related	5N92 5N9B
Descriptor	Interleukin-17A, Interleukin-17 receptor A, Interleukin-17F, ... (5 entities in total)
Functional Keywords	cystine-knot, fibronectin type iii, cytokine
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	135776.32
Authors	Rondeau, J.-M.,Goepfert, A. (deposition date: 2017-02-28, release date: 2017-09-06, Last modification date: 2024-01-17)
Primary citation	Goepfert, A.,Lehmann, S.,Wirth, E.,Rondeau, J.M. The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties. Sci Rep, 7:8906-8906, 2017 Cited by PubMed: 28827714 DOI: 10.1038/s41598-017-08360-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation