5NAN
Crystal Structure of human IL-17AF in complex with human IL-17RA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Interleukin-17A | polymer | 132 | 15146.1 | 2 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (Human) | IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | B, C (B, C) | Interleukin-17 receptor A | polymer | 311 | 36199.8 | 2 | UniProt (Q96F46) Pfam (PF16556) Pfam (PF16578) | Homo sapiens (Human) | IL-17RA,CDw217 |
| 3 | E, F (E, F) | Interleukin-17F | polymer | 139 | 15695.9 | 2 | UniProt (Q96PD4) Pfam (PF06083) | Homo sapiens (Human) | IL-17F,Cytokine ML-1 |
| 4 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-galactopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G49445EF) | |||
| 5 | H, I, J, K, L (B, C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
B, C: 33 - 320 (UniProt: Q96F46)
E, F: 31 - 163 (UniProt: Q96PD4)
| PDB | External Database | Details |
|---|---|---|
| Glu 321 | - | expression tag |
| Phe 322 | - | expression tag |
| Arg 323 | - | expression tag |
| His 324 | - | expression tag |
| Asp 325 | - | expression tag |
| Ser 326 | - | expression tag |
| Gly 327 | - | expression tag |
| Gly 328 | - | expression tag |
| Gly 329 | - | expression tag |
| Leu 330 | - | expression tag |
| Asn 331 | - | expression tag |
| Asp 332 | - | expression tag |
| Ile 333 | - | expression tag |
| Phe 334 | - | expression tag |
| Glu 335 | - | expression tag |
| Ala 336 | - | expression tag |
| Gln 337 | - | expression tag |
| Lys 338 | - | expression tag |
| Ile 339 | - | expression tag |
| Glu 340 | - | expression tag |
| Trp 341 | - | expression tag |
| His 342 | - | expression tag |
| Glu 343 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 25 | - | expression tag |
| Phe 26 | - | expression tag |
| Arg 27 | - | expression tag |
| His 28 | - | expression tag |
| Asp 29 | - | expression tag |
| Ser 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 134083.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 135776.3 |
