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5N9B

Crystal Structure of unliganded human IL-17RA

Summary for 5N9B
Entry DOI10.2210/pdb5n9b/pdb
Related5N92
DescriptorInterleukin-17 receptor A, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordsfibronectin type iii, signaling protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight34084.45
Authors
Rondeau, J.-M.,Goepfert, A. (deposition date: 2017-02-24, release date: 2018-06-13, Last modification date: 2024-01-31)
Primary citationGoepfert, A.,Barske, C.,Lehmann, S.,Wirth, E.,Willemsen, J.,Gudjonsson, J.E.,Ward, N.L.,Sarkar, M.K.,Hemmig, R.,Kolbinger, F.,Rondeau, J.M.
IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling.
Cell Rep, 41:111489-111489, 2022
Cited by
PubMed: 36260993
DOI: 10.1016/j.celrep.2022.111489
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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