5N4E

Prolyl oligopeptidase B from Galerina marginata bound to 35mer hydrolysis and macrocyclization substrate - H698A mutant

Summary for 5N4E

Entry DOI	10.2210/pdb5n4e/pdb
Descriptor	Prolyl oligopeptidase, Alpha-amanitin proprotein, GLYCEROL, ... (4 entities in total)
Functional Keywords	amanitin biosynthesis, prolyl oligopeptidase, hydrolase, macrocyclase, peptidase, beta-propeller, closed form
Biological source	Galerina marginata More
Total number of polymer chains	4
Total formula weight	179076.24
Authors	Czekster, C.M.,McMahon, S.A.,Ludewig, H.,Naismith, J.H. (deposition date: 2017-02-10, release date: 2017-11-01, Last modification date: 2019-10-16)
Primary citation	Czekster, C.M.,Ludewig, H.,McMahon, S.A.,Naismith, J.H. Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates. Nat Commun, 8:1045-1045, 2017 Cited by PubMed: 29051530 DOI: 10.1038/s41467-017-00862-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation