5N47
Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin
Summary for 5N47
Entry DOI | 10.2210/pdb5n47/pdb |
Related | 4GH7 5N48 |
Descriptor | Neutrophil gelatinase-associated lipocalin, Fibronectin (2 entities in total) |
Functional Keywords | lipocalin, anticalin, lipocalin-based binding protein, protein binding, human fibronectin, oncofetal splice variant, fn type iii domain, extra-domain b, eiiib, ed-b, extracellular matrix, structural protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted : P80188 Secreted, extracellular space, extracellular matrix: P02751 |
Total number of polymer chains | 6 |
Total formula weight | 157687.83 |
Authors | Schiefner, A.,Skerra, A. (deposition date: 2017-02-10, release date: 2018-02-14, Last modification date: 2024-01-17) |
Primary citation | Schiefner, A.,Gebauer, M.,Richter, A.,Skerra, A. Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen. Structure, 26:649-656.e3, 2018 Cited by PubMed: 29526433DOI: 10.1016/j.str.2018.02.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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