5MU6
Human N-myristoyltransferase (NMT1) with Myristoyl-CoA and IMP-1088 inhibitor bound
Summary for 5MU6
Entry DOI | 10.2210/pdb5mu6/pdb |
Related | 4C2Y 4C2Z |
Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | n-myristoylation, inhibitor, rhinovirus capsule assembly, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 94186.52 |
Authors | Perez-Dorado, I.,Bell, A.S.,Tate, E.W. (deposition date: 2017-01-12, release date: 2018-02-14, Last modification date: 2024-01-17) |
Primary citation | Mousnier, A.,Bell, A.S.,Swieboda, D.P.,Morales-Sanfrutos, J.,Perez-Dorado, I.,Brannigan, J.A.,Newman, J.,Ritzefeld, M.,Hutton, J.A.,Guedan, A.,Asfor, A.S.,Robinson, S.W.,Hopkins-Navratilova, I.,Wilkinson, A.J.,Johnston, S.L.,Leatherbarrow, R.J.,Tuthill, T.J.,Solari, R.,Tate, E.W. Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10:599-606, 2018 Cited by PubMed: 29760414DOI: 10.1038/s41557-018-0039-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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