5MU6
Human N-myristoyltransferase (NMT1) with Myristoyl-CoA and IMP-1088 inhibitor bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycylpeptide N-tetradecanoyltransferase 1 | polymer | 391 | 45453.3 | 2 | UniProt (P30419) Pfam (PF01233) Pfam (PF02799) | Homo sapiens (Human) | Myristoyl-CoA:protein N-myristoyltransferase 1,Type I N-myristoyltransferase,Peptide N-myristoyltransferase 1 |
| 2 | C, H (A, B) | TETRADECANOYL-COA | non-polymer | 977.9 | 2 | Chemie (MYA) | |||
| 3 | D, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, F, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | G, L (A, B) | 1-[5-[3,4-bis(fluoranyl)-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine | non-polymer | 453.5 | 2 | Chemie (KFK) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 456 | Chemie (HOH) |
Sequence modifications
A, B: 109 - 496 (UniProt: P30419)
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | expression tag |
| Pro 107 | - | expression tag |
| His 108 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90906.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3279.8 | |
| All* | Total formula weight | 94186.5 |
