5MSA
Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide
Summary for 5MSA
Entry DOI | 10.2210/pdb5msa/pdb |
Related | 5LLC 5LLE 5LLG 5LLH 5LLN 5LLO 5LLP |
Descriptor | Carbonic anhydrase 12, ZINC ION, 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide, ... (7 entities in total) |
Functional Keywords | drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Membrane; Single-pass type I membrane protein: O43570 |
Total number of polymer chains | 4 |
Total formula weight | 122889.76 |
Authors | Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2017-01-02, release date: 2018-01-17, Last modification date: 2024-10-09) |
Primary citation | Smirnov, A.,Manakova, E.,Grazulis, S.,Matulis, D.,Dudutiene, V. Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide To be published, |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
Download full validation report