Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5MSA

Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide

Summary for 5MSA
Entry DOI10.2210/pdb5msa/pdb
Related5LLC 5LLE 5LLG 5LLH 5LLN 5LLO 5LLP
DescriptorCarbonic anhydrase 12, ZINC ION, 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide, ... (7 entities in total)
Functional Keywordsdrug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase
Biological sourceHomo sapiens (Human)
Cellular locationMembrane; Single-pass type I membrane protein: O43570
Total number of polymer chains4
Total formula weight122889.76
Authors
Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2017-01-02, release date: 2018-01-17, Last modification date: 2024-10-09)
Primary citationSmirnov, A.,Manakova, E.,Grazulis, S.,Matulis, D.,Dudutiene, V.
Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide
To be published,
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon