5MLS

Thrombin Mutant A190S in complex with (S)-1-(D-phenylalanyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide

5MLS の概要

• エントリーDOI: 10.2210/pdb5mls/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000593
• 分子名称: Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total)
• 機能のキーワード: coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, preorganization, glycosilation, blood, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36598.87

構造登録者

Marca, A.,Sandner, A.,Heine, A.,Klebe, G. (登録日: 2016-12-07, 公開日: 2017-12-20, 最終更新日: 2018-06-13)

• 主引用文献: Marca, A.,Sandner, A.,Heine, A.,Klebe, G.; Thrombin Mutante A190S in complex with (S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide; to be published,

実験手法

X-RAY DIFFRACTION (1.62 Å)