5M5F

Thermolysin in complex with inhibitor and krypton

Summary for 5M5F

Entry DOI	10.2210/pdb5m5f/pdb
Descriptor	Thermolysin, ZINC ION, CALCIUM ION, ... (8 entities in total)
Functional Keywords	hydrolase, metalloprotease, hydrolase inhibitor complex
Biological source	Bacillus thermoproteolyticus
Cellular location	Secreted: P00800
Total number of polymer chains	1
Total formula weight	35665.75
Authors	Krimmer, S.G.,Cramer, J.,Heine, A.,Klebe, G. (deposition date: 2016-10-21, release date: 2017-08-16, Last modification date: 2024-01-17)
Primary citation	Krimmer, S.G.,Cramer, J.,Schiebel, J.,Heine, A.,Klebe, G. How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S1' Pocket of Thermolysin. J. Am. Chem. Soc., 139:10419-10431, 2017 Cited by PubMed: 28696673 DOI: 10.1021/jacs.7b05028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.33 Å)

Structure validation