5LSJ
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX
Summary for 5LSJ
Entry DOI | 10.2210/pdb5lsj/pdb |
Descriptor | Protein MIS12 homolog, Polyamine-modulated factor 1, Kinetochore-associated protein DSN1 homolog, ... (5 entities in total) |
Functional Keywords | alpha-helical, cell cycle |
Biological source | Homo sapiens (Human) More |
Cellular location | Chromosome, centromere, kinetochore : Q9H081 Nucleus : Q6P1K2 Q9H410 Q96IY1 Q03188 |
Total number of polymer chains | 10 |
Total formula weight | 173558.23 |
Authors | Vetter, I.R.,Petrovic, A.,Keller, J.,Liu, Y. (deposition date: 2016-09-02, release date: 2016-11-16, Last modification date: 2024-01-17) |
Primary citation | Petrovic, A.,Keller, J.,Liu, Y.,Overlack, K.,John, J.,Dimitrova, Y.N.,Jenni, S.,van Gerwen, S.,Stege, P.,Wohlgemuth, S.,Rombaut, P.,Herzog, F.,Harrison, S.C.,Vetter, I.R.,Musacchio, A. Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell, 167:1028-1040.e15, 2016 Cited by PubMed: 27881301DOI: 10.1016/j.cell.2016.10.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
Download full validation report