5LSJ

CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000070	biological_process	mitotic sister chromatid segregation
A	0000278	biological_process	mitotic cell cycle
A	0000444	cellular_component	MIS12/MIND type complex
A	0000775	cellular_component	chromosome, centromeric region
A	0000776	cellular_component	kinetochore
A	0000922	cellular_component	spindle pole
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005694	cellular_component	chromosome
A	0005829	cellular_component	cytosol
A	0007049	biological_process	cell cycle
A	0007059	biological_process	chromosome segregation
A	0008608	biological_process	attachment of spindle microtubules to kinetochore
A	0051301	biological_process	cell division
A	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
A	0051382	biological_process	kinetochore assembly
B	0000444	cellular_component	MIS12/MIND type complex
C	0000070	biological_process	mitotic sister chromatid segregation
C	0000278	biological_process	mitotic cell cycle
C	0000444	cellular_component	MIS12/MIND type complex
C	0000775	cellular_component	chromosome, centromeric region
C	0000776	cellular_component	kinetochore
C	0000922	cellular_component	spindle pole
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0005829	cellular_component	cytosol
C	0007049	biological_process	cell cycle
C	0007059	biological_process	chromosome segregation
C	0008608	biological_process	attachment of spindle microtubules to kinetochore
C	0051301	biological_process	cell division
C	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
C	0051382	biological_process	kinetochore assembly
D	0000444	cellular_component	MIS12/MIND type complex
D	0007059	biological_process	chromosome segregation
D	0051301	biological_process	cell division
E	0000444	cellular_component	MIS12/MIND type complex
F	0000444	cellular_component	MIS12/MIND type complex
F	0007059	biological_process	chromosome segregation
F	0051301	biological_process	cell division
G	0000070	biological_process	mitotic sister chromatid segregation
G	0000776	cellular_component	kinetochore
N	0000070	biological_process	mitotic sister chromatid segregation
N	0000776	cellular_component	kinetochore

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
P	LYS45
F	SER331
Q	LYS45

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	LYS253
F	LYS253

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