Summary for 5LJ0
| Descriptor | ATPase family AAA domain-containing protein 2, 1,2-ETHANEDIOL, 8-(((3R,4R,5S)-3-((4,4-difluorocyclohexyl)methoxy)-5-methoxypiperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one, ... (5 entities in total) |
|---|---|
| Functional Keywords | inhibitor, atad2, bromodomain, epigenetics, atpase family aaa domain-containing protein 2, transcription |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus Q6PL18 |
| Total number of polymer chains | 1 |
| Total molecular weight | 16325.46 |
| Authors | Chung, C. (deposition date: 2016-07-17, release date: 2016-08-31, Last modification date: 2016-09-14) |
| Primary citation | Bamborough, P.,Chung, C.W.,Demont, E.H.,Furze, R.C.,Bannister, A.J.,Che, K.H.,Diallo, H.,Douault, C.,Grandi, P.,Kouzarides, T.,Michon, A.M.,Mitchell, D.J.,Prinjha, R.K.,Rau, C.,Robson, S.,Sheppard, R.J.,Upton, R.,Watson, R.J. A Chemical Probe for the ATAD2 Bromodomain. Angew.Chem.Int.Ed.Engl., 55:11382-11386, 2016 PubMed: 27530368 (PDB entries with the same primary citation) DOI: 10.1002/anie.201603928  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (1.82 Å) |
