5LG3
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with chlorpromazine
Summary for 5LG3
| Entry DOI | 10.2210/pdb5lg3/pdb |
| Descriptor | Gamma-aminobutyric-acid receptor subunit beta-1, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine (2 entities in total) |
| Functional Keywords | ion channel, transport protein, membrane protein |
| Biological source | Dickeya dadantii (strain 3937) |
| Total number of polymer chains | 10 |
| Total formula weight | 357022.31 |
| Authors | Nys, M.,Wijckmans, E.,Farinha, A.,Brams, M.,Spurny, R.,Ulens, C. (deposition date: 2016-07-05, release date: 2016-10-26, Last modification date: 2024-01-31) |
| Primary citation | Nys, M.,Wijckmans, E.,Farinha, A.,Yoluk, O.,Andersson, M.,Brams, M.,Spurny, R.,Peigneur, S.,Tytgat, J.,Lindahl, E.,Ulens, C. Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine. Proc.Natl.Acad.Sci.USA, 113:E6696-E6703, 2016 Cited by PubMed: 27791038DOI: 10.1073/pnas.1603101113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.567 Å) |
Structure validation
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