5LBX
Structure of the T175V Etr1p mutant in the trigonal form P312 in complex with NADP and crotonyl-CoA
Summary for 5LBX
| Entry DOI | 10.2210/pdb5lbx/pdb |
| Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | negative catalysis, enzyme, nadp, mitochondria, mutant, crotonyl-coa, reductase, oxidoreductase |
| Biological source | Candida tropicalis (Yeast) |
| Cellular location | Mitochondrion : Q8WZM3 |
| Total number of polymer chains | 2 |
| Total formula weight | 88616.62 |
| Authors | Wagner, T.,Rosenthal, R.G.,Voegeli, B.,Shima, S.,Erb, T.J. (deposition date: 2016-06-17, release date: 2017-05-10, Last modification date: 2024-01-10) |
| Primary citation | Rosenthal, R.G.,Vogeli, B.,Wagner, T.,Shima, S.,Erb, T.J. A conserved threonine prevents self-intoxication of enoyl-thioester reductases. Nat. Chem. Biol., 13:745-749, 2017 Cited by PubMed: 28504678DOI: 10.1038/nchembio.2375 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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