Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| A | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| B | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue NAP A 401 |
| Chain | Residue |
| A | PRO69 |
| A | ARG224 |
| A | TYR296 |
| A | GLY297 |
| A | MET299 |
| A | PHE321 |
| A | VAL323 |
| A | LYS381 |
| A | COO410 |
| A | HOH527 |
| A | HOH534 |
| A | VAL171 |
| A | HOH573 |
| A | ASN172 |
| A | VAL175 |
| A | THR199 |
| A | SER200 |
| A | ALA201 |
| A | VAL202 |
| A | ARG222 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | SER125 |
| A | HIS126 |
| A | VAL127 |
| A | LYS331 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | SER250 |
| A | ARG251 |
| A | GLU252 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | VAL242 |
| A | GLN247 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | LYS145 |
| A | GLN151 |
| A | ASN155 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | GLN33 |
| A | HIS34 |
| A | LYS85 |
| A | HOH544 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | ARG224 |
| A | ASN226 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| B | LYS278 |
| B | ARG285 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 409 |
| Chain | Residue |
| A | ASN288 |
| A | ASN289 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue COO A 410 |
| Chain | Residue |
| A | SER70 |
| A | ASN73 |
| A | TYR79 |
| A | GLY297 |
| A | GLY298 |
| A | THR324 |
| A | NAP401 |
| A | HOH569 |
| B | THR308 |
| B | SER309 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 411 |
| Chain | Residue |
| A | LYS153 |
| A | LYS153 |
| site_id | AD3 |
| Number of Residues | 20 |
| Details | binding site for residue NAP B 401 |
| Chain | Residue |
| B | VAL171 |
| B | ASN172 |
| B | VAL175 |
| B | THR199 |
| B | SER200 |
| B | ALA201 |
| B | VAL202 |
| B | ARG222 |
| B | ARG224 |
| B | TYR296 |
| B | GLY297 |
| B | MET299 |
| B | PHE321 |
| B | VAL323 |
| B | LYS381 |
| B | COO407 |
| B | HOH528 |
| B | HOH541 |
| B | HOH551 |
| B | HOH553 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | GLN33 |
| B | HIS34 |
| B | LYS85 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | VAL242 |
| B | GLN247 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | ARG224 |
| B | ASN226 |
| B | VAL230 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 405 |
| Chain | Residue |
| B | ARG222 |
| B | LYS378 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| B | ASN288 |
| B | ASN289 |
| B | HOH504 |
| site_id | AD9 |
| Number of Residues | 11 |
| Details | binding site for residue COO B 407 |
| Chain | Residue |
| A | THR308 |
| A | SER309 |
| B | SER70 |
| B | ASN73 |
| B | TYR79 |
| B | GLY298 |
| B | MET299 |
| B | PHE301 |
| B | THR324 |
| B | NAP401 |
| B | HOH503 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"25867044","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12614607","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12890667","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| A | TYR79 | electrostatic stabiliser, increase electrophilicity |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| B | TYR79 | electrostatic stabiliser, increase electrophilicity |
