5LAI

Ligand-induced aziridine-formation at the yeast proteasomal subunit beta5 by sulfonate esters

Summary for 5LAI

• Entry DOI: 10.2210/pdb5lai/pdb
• Related: 4R17 5CZ4
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (17 entities in total)
• Functional Keywords: proteasome, fluorescent probes, binding analysis, umpolung, crosslink, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Cellular location: Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
• Total number of polymer chains: 28
• Total formula weight: 731520.33

Authors

Groll, M.,Dubiella, C.,Cui, H. (deposition date: 2016-06-14, release date: 2017-04-26, Last modification date: 2024-01-10)

• Primary citation: Dubiella, C.,Cui, H.,Groll, M.; Tunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome.; Angew. Chem. Int. Ed. Engl., 55:13330-13334, 2016; PubMed: 27709817; DOI: 10.1002/anie.201605753

Experimental method

X-RAY DIFFRACTION (2.5 Å)