5L6D

Crystal structure of the human METTL3-METTL14 complex bound to SAH

Summary for 5L6D

• Entry DOI: 10.2210/pdb5l6d/pdb
• Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total)
• Functional Keywords: rna methyltransferase n6-adenine methylation rossmann fold, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q86U44 Q9HCE5
• Total number of polymer chains: 2
• Total formula weight: 59844.46

Authors

Sledz, P.,Jinek, M. (deposition date: 2016-05-29, release date: 2016-10-12)

• Primary citation: Sledz, P.,Jinek, M.; Structural insights into the molecular mechanism of the m(6)A writer complex.; Elife, 5:-, 2016; PubMed: 27627798; DOI: 10.7554/eLife.18434

Experimental method

X-RAY DIFFRACTION (1.852 Å)