5L6D
Crystal structure of the human METTL3-METTL14 complex bound to SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N6-adenosine-methyltransferase 70 kDa subunit | polymer | 227 | 25886.6 | 1 | UniProt (Q86U44) Pfam (PF05063) | Homo sapiens (Human) | MT-A70,Methyltransferase-like protein 3 |
| 2 | B (B) | N6-adenosine-methyltransferase subunit METTL14 | polymer | 289 | 33490.1 | 1 | UniProt (Q9HCE5) Pfam (PF05063) | Homo sapiens (Human) | Methyltransferase-like protein 14 |
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (B) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59376.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 467.8 | |
| All* | Total formula weight | 59844.5 |
