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5L46

Crystal structure of human dimethylglycine-dehydrogenase

Summary for 5L46
Entry DOI10.2210/pdb5l46/pdb
DescriptorDimethylglycine dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordselectron transfer, covalent flavinylation, oxidoreductase, one-carbon metabolism
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion: Q9UI17
Total number of polymer chains2
Total formula weight190190.12
Authors
Hromic, A.,Pavkov-Keller, T.,Gruber, K. (deposition date: 2016-05-25, release date: 2016-08-17, Last modification date: 2024-01-10)
Primary citationAugustin, P.,Hromic, A.,Pavkov-Keller, T.,Gruber, K.,Macheroux, P.
Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant.
Febs J., 283:3587-3603, 2016
Cited by
PubMed: 27486859
DOI: 10.1111/febs.13828
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.09 Å)
Structure validation

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