5KQ4

Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2 and synthetic cap analog

Summary for 5KQ4

• Entry DOI: 10.2210/pdb5kq4/pdb
• Related: 5KQ1
• Descriptor: mRNA-decapping enzyme subunit 1, Proline-rich nuclear receptor coactivator 2, mRNA decapping complex subunit 2, ... (5 entities in total)
• Functional Keywords: decapping mrna decay nudix cap analog, hydrolase
• Biological source: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast); More
• Total number of polymer chains: 6
• Total formula weight: 97154.38

Authors

Mugridge, J.S.,Ziemniak, M.,Jemielity, J.,Gross, J.D. (deposition date: 2016-07-05, release date: 2016-10-05, Last modification date: 2023-10-04)

• Primary citation: Mugridge, J.S.,Ziemniak, M.,Jemielity, J.,Gross, J.D.; Structural basis of mRNA-cap recognition by Dcp1-Dcp2.; Nat.Struct.Mol.Biol., 23:987-994, 2016; PubMed: 27694842; DOI: 10.1038/nsmb.3301

Experimental method

X-RAY DIFFRACTION (2.56 Å)