5KEG
Crystal structure of APOBEC3A in complex with a single-stranded DNA
Summary for 5KEG
Entry DOI | 10.2210/pdb5keg/pdb |
Descriptor | DNA dC->dU-editing enzyme APOBEC-3A, DNA (5'-D(*TP*TP*CP*TP*T)-3'), ZINC ION, ... (6 entities in total) |
Functional Keywords | apobec3a, dna cytidine deaminase complex with a substrate dna, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27944.14 |
Authors | Kouno, T.,Hilbert, B.J.,Silvas, T.,Royer, W.E.,Matsuo, H.,Schiffer, C.A. (deposition date: 2016-06-09, release date: 2017-05-10, Last modification date: 2023-09-27) |
Primary citation | Kouno, T.,Silvas, T.V.,Hilbert, B.J.,Shandilya, S.M.D.,Bohn, M.F.,Kelch, B.A.,Royer, W.E.,Somasundaran, M.,Kurt Yilmaz, N.,Matsuo, H.,Schiffer, C.A. Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity. Nat Commun, 8:15024-15024, 2017 Cited by PubMed: 28452355DOI: 10.1038/ncomms15024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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