5KEG
Crystal structure of APOBEC3A in complex with a single-stranded DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA dC->dU-editing enzyme APOBEC-3A | polymer | 203 | 23300.3 | 1 | UniProt (P31941) Pfam (PF05240) | Homo sapiens (Human) | A3A,Phorbolin-1 |
| 2 | B (B) | DNA (5'-D(*TP*TP*CP*TP*T)-3') | polymer | 15 | 4502.9 | 1 | synthetic construct | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 1 - 199 (UniProt: P31941)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 72 | Glu 72 | engineered mutation |
| Ala 171 | Cys 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27803.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 140.9 | |
| All* | Total formula weight | 27944.1 |
