5KDL
Crystal structure of the 4 alanine insertion variant of the Gi alpha1 subunit bound to GTPgammaS
Summary for 5KDL
Entry DOI | 10.2210/pdb5kdl/pdb |
Related | 5KDO |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | heterotrimeric g protein g protein coupled receptors g protein activation g protein structure gdp release, signaling protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 2 |
Total formula weight | 82493.80 |
Authors | Kaya, A.I.,Lokits, A.D.,Gilbert, J.,Iverson, T.M.,Meiler, J.,Hamm, H.E. (deposition date: 2016-06-08, release date: 2016-08-03, Last modification date: 2023-09-27) |
Primary citation | Kaya, A.I.,Lokits, A.D.,Gilbert, J.A.,Iverson, T.M.,Meiler, J.,Hamm, H.E. A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor. J.Biol.Chem., 291:19674-19686, 2016 Cited by PubMed: 27462082DOI: 10.1074/jbc.M116.745513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.665 Å) |
Structure validation
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