5KCO

SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy

5KCO の概要

• エントリーDOI: 10.2210/pdb5kco/pdb
• 関連するPDBエントリー: 5KCH
• 分子名称: Histone-lysine N-methyltransferase SETDB1, SULFATE ION, ~{N}-(4-chlorophenyl)methanesulfonamide, ... (6 entities in total)
• 機能のキーワード: fragment screening, diamond i04-1 xchem, pandda, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus: Q15047
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31484.50

構造登録者

Tempel, W.,Harding, R.J.,Mader, P.,Dobrovetsky, E.,Walker, J.R.,Brown, P.J.,Schapira, M.,Collins, P.,Pearce, N.,Brandao-Neto, J.,Douangamath, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Santhakumar, V.,Structural Genomics Consortium (SGC) (登録日: 2016-06-06, 公開日: 2016-07-27, 最終更新日: 2023-09-27)

• 主引用文献: Tempel, W.,Harding, R.J.,Mader, P.,Dobrovetsky, E.,Walker, J.R.,Brown, P.J.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Santhakumar, S.,Structural Genomics Consortium (SGC); SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy; To Be Published,

実験手法

X-RAY DIFFRACTION (1.47 Å)