5KA0
Protein Tyrosine Phosphatase 1B Delta helix 7, open state
Summary for 5KA0
Entry DOI | 10.2210/pdb5ka0/pdb |
Related | 5K9V 5K9W 5KA1 5KA2 5KA3 5KA4 5KA7 5KA8 5KA9 5KAA 5KAB 5KAC 5KAD |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... (5 entities in total) |
Functional Keywords | protein tyrosine phosphatase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34250.90 |
Authors | Choy, M.S.,Peti, W.,Page, R. (deposition date: 2016-06-01, release date: 2017-03-01, Last modification date: 2023-09-27) |
Primary citation | Choy, M.S.,Li, Y.,Machado, L.E.,Kunze, M.B.,Connors, C.R.,Wei, X.,Lindorff-Larsen, K.,Page, R.,Peti, W. Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery. Mol. Cell, 65:644-658.e5, 2017 Cited by PubMed: 28212750DOI: 10.1016/j.molcel.2017.01.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.991 Å) |
Structure validation
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