5K8X

Crystal structure of mouse CARM1 in complex with inhibitor U3

Summary for 5K8X

• Entry DOI: 10.2210/pdb5k8x/pdb
• Descriptor: Histone-arginine methyltransferase CARM1, [[[(~{E})-3-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]prop-2-enyl]amino]-azanyl-methylidene]azanium, 1,2-ETHANEDIOL, ... (9 entities in total)
• Functional Keywords: protein arginine methyltransferase, catalytic domain, chromatin regulator, mrna processing, mrna splicing, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase
• Biological source: Mus musculus (Mouse)
• Cellular location: Nucleus: Q9WVG6
• Total number of polymer chains: 4
• Total formula weight: 167382.31

Authors

Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Hassenboehler, P.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J. (deposition date: 2016-05-31, release date: 2017-06-21, Last modification date: 2024-01-10)

• Primary citation: Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J.; Crystal structure of mouse CARM1 in complex with inhibitor U3; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.991 Å)