5J5F
X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with N4,N4-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine
Summary for 5J5F
| Entry DOI | 10.2210/pdb5j5f/pdb |
| Related | 4QAA 4QAB 4QAC 5J5G 5J5H 5J5I |
| Descriptor | Acetylcholine-binding protein, PHOSPHATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | acetylcholine-binding protein |
| Biological source | Lymnaea stagnalis (Great pond snail) |
| Cellular location | Secreted: P58154 |
| Total number of polymer chains | 10 |
| Total formula weight | 255858.66 |
| Authors | Kaczanowska, K.,Camacho Hernandez, G.A.,Harel, M.,Taylor, P. (deposition date: 2016-04-02, release date: 2017-03-08, Last modification date: 2023-09-27) |
| Primary citation | Kaczanowska, K.,Camacho Hernandez, G.A.,Bendiks, L.,Kohs, L.,Cornejo-Bravo, J.M.,Harel, M.,Finn, M.G.,Taylor, P. Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139:3676-3684, 2017 Cited by PubMed: 28221788DOI: 10.1021/jacs.6b10746 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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