5J5F

X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with N4,N4-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Acetylcholine-binding protein	polymer	218	24859.5	10	UniProt (P58154) Pfam (PF02931) In PDB	Lymnaea stagnalis (Great pond snail)	AchBP
2	F, H, A, I, B...	PHOSPHATE ION	non-polymer		95.0	11	Chemie (PO4)
3	F, G, H, A, I...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
4	F, G, H, A, I...	N~4~,N~4~-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine	non-polymer		374.5	10	Chemie (6GH)
5	F, H	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	H	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
7		water	water		18.0	1266	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 210 (UniProt: P58154)

PDB	External Database	Details
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	248595.0
Non-Polymers*	Number of molecules	34
	Total formula weight	7263.7
All*	Total formula weight	255858.7

*Water molecules are not included.