5ICS
Crystal structure of 17beta-hydroxysteroid dehydrogenase type 14 apoenzyme.
Summary for 5ICS
| Entry DOI | 10.2210/pdb5ics/pdb |
| Related | 5EN4 |
| Descriptor | 17-beta-hydroxysteroid dehydrogenase 14 (2 entities in total) |
| Functional Keywords | apoenzyme, hydroxysteroid dehydrogenase, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm : Q9BPX1 |
| Total number of polymer chains | 4 |
| Total formula weight | 114674.87 |
| Authors | Bertoletti, N.,Marchais-Oberwinkler, S.,Heine, A.,Klebe, G. (deposition date: 2016-02-23, release date: 2016-07-13, Last modification date: 2024-01-10) |
| Primary citation | Bertoletti, N.,Braun, F.,Lepage, M.,Moller, G.,Adamski, J.,Heine, A.,Klebe, G.,Marchais-Oberwinkler, S. New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor. J.Med.Chem., 59:6961-6967, 2016 Cited by PubMed: 27362750DOI: 10.1021/acs.jmedchem.6b00293 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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