5HY8

Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes

5HY8 の概要

• エントリーDOI: 10.2210/pdb5hy8/pdb
• 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
• 機能のキーワード: glycation, hemoglobin, diabetes, oxidative stress, oxygen transport
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 162344.24

構造登録者

Saraswathi, N.T.,Pannu, N.S.,Syakhovich, V.E.,Saurabh, A.,Bokut, S.B.,Moras, D.,Ruff, M. (登録日: 2016-02-01, 公開日: 2017-02-01, 最終更新日: 2024-01-10)

• 主引用文献: Saraswathi, N.T.,Pannu, N.S.,Syakhovich, V.E.,Saurabh, A.,Bokut, S.B.,Moras, D.,Ruff, M.; Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes; To Be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)