5HKG
Total chemical synthesis, refolding and crystallographic structure of a fully active immunophilin: calstabin 2 (FKBP12.6).
Summary for 5HKG
Entry DOI | 10.2210/pdb5hkg/pdb |
Related | 1C9H |
Descriptor | Peptidyl-prolyl cis-trans isomerase FKBP1B, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | synthetic protein, refolding, immunophilin, isomerase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P68106 |
Total number of polymer chains | 1 |
Total formula weight | 12936.11 |
Authors | Sirigu, S.,Huet, T.,Bacchi, M.,Jullian, M.,Fould, B.,Ferry, G.,Vuillard, L.,Chavas, L.,Puget, K.,Nosjean, O.,Boutin, J.A. (deposition date: 2016-01-14, release date: 2016-10-05, Last modification date: 2024-01-10) |
Primary citation | Bacchi, M.,Jullian, M.,Sirigu, S.,Fould, B.,Huet, T.,Bruyand, L.,Antoine, M.,Vuillard, L.,Ronga, L.,Chavas, L.M.,Nosjean, O.,Ferry, G.,Puget, K.,Boutin, J.A. Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6). Protein Sci., 25:2225-2242, 2016 Cited by PubMed: 27670942DOI: 10.1002/pro.3051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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