5HKG
Total chemical synthesis, refolding and crystallographic structure of a fully active immunophilin: calstabin 2 (FKBP12.6).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peptidyl-prolyl cis-trans isomerase FKBP1B | polymer | 107 | 11667.3 | 1 | UniProt (P68106) Pfam (PF00254) In PDB | Homo sapiens (Human) | PPIase FKBP1B,12.6 kDa FK506-binding protein,FKBP-12.6,FK506-binding protein 1B,FKBP-1B,Immunophilin FKBP12.6,Rotamase,h-FKBP-12 |
| 2 | A | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | non-polymer | 914.2 | 1 | Chemie (RAP) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11667.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1268.8 | |
| All* | Total formula weight | 12936.1 |
