5HK5
Structure of the Grem2-GDF5 Inhibitory Complex
Summary for 5HK5
Entry DOI | 10.2210/pdb5hk5/pdb |
Descriptor | Gremlin-2, Growth/differentiation factor 5 (2 entities in total) |
Functional Keywords | dan-family, bone morphogenetic proteins, cytokine |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 122424.48 |
Authors | Nolan, K.,Thompson, T.B.,Read, R.J. (deposition date: 2016-01-13, release date: 2016-08-24, Last modification date: 2023-09-27) |
Primary citation | Nolan, K.,Kattamuri, C.,Rankin, S.A.,Read, R.J.,Zorn, A.M.,Thompson, T.B. Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism. Cell Rep, 16:2077-2086, 2016 Cited by PubMed: 27524626DOI: 10.1016/j.celrep.2016.07.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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