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5HK5

Structure of the Grem2-GDF5 Inhibitory Complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1E, F, G, HGremlin-2polymer14717007.54UniProt (O88273)
Pfam (PF03045)
In PDB
Mus musculus (Mouse)Cysteine knot superfamily 1,BMP antagonist 2,Protein related to DAN and cerberus,PRDC
2A, B, C, DGrowth/differentiation factor 5polymer12013598.64UniProt (P43026)
Pfam (PF00019)
In PDB
Homo sapiens (Human)GDF-5,Bone morphogenetic protein 14,BMP-14,Cartilage-derived morphogenetic protein 1,CDMP-1,Lipopolysaccharide-associated protein 4,LPS-associated protein 4,Radotermin
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight122424.5
All*Total formula weight122424.5
*Water molecules are not included.

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PDB entries from 2024-10-09

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