5HI6

The high resolution structure of dihydrofolate reductase from Yersinia pestis complex with methotrexate as closed form

Summary for 5HI6

Entry DOI	10.2210/pdb5hi6/pdb
Descriptor	Dihydrofolate reductase, METHOTREXATE, CALCIUM ION, ... (6 entities in total)
Functional Keywords	structural genomics, center for structural genomics of infectious diseases, csgid, dihydrofolate reductase, yersinia pestis, oxidoreductase
Biological source	Yersinia pestis CO92
Total number of polymer chains	2
Total formula weight	38455.89
Authors	Chang, C.,Maltseva, N.,Kim, Y.,Makowska-Grzyska, M.,Mulligan, R.,Papazisi, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2016-01-11, release date: 2016-02-03, Last modification date: 2024-10-30)
Primary citation	Chang, C.,Maltseva, N.,Kim, Y.,Makowska-Grzyska, M.,Mulligan, R.,Papazisi, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) The high resolution structure of dihydrofolate reductase from Yersinia pestis complex with methotrexate as closed form To Be Published,
Experimental method	X-RAY DIFFRACTION (2.051 Å)

Structure validation