5HBT

Complex structure of Fab35 and human nAChR alpha1

Summary for 5HBT

• Entry DOI: 10.2210/pdb5hbt/pdb
• Related: 5HBV
• Descriptor: Acetylcholine receptor subunit alpha 1, Fab35, Light Chain, Fab35, Heavy Chain, ... (6 entities in total)
• Functional Keywords: nicotinic acetylcholine receptor alpha1, fab35, complex, myasthenia gravis, transport protein-toxin complex, transport protein/toxin
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 81492.36

Authors

Noridomi, K.,Watanabe, G.,Hansen, M.N.,Han, G.W.,Chen, L. (deposition date: 2016-01-02, release date: 2017-05-03, Last modification date: 2020-07-29)

• Primary citation: Noridomi, K.,Watanabe, G.,Hansen, M.N.,Han, G.W.,Chen, L.; Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications.; Elife, 6:-, 2017; PubMed: 28440223; DOI: 10.7554/eLife.23043

Experimental method

X-RAY DIFFRACTION (2.61 Å)