5HBT
Complex structure of Fab35 and human nAChR alpha1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0030550 | molecular_function | acetylcholine receptor inhibitor activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0022848 | molecular_function | acetylcholine-gated monoatomic cation-selective channel activity |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0045211 | cellular_component | postsynaptic membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00236 |
| Number of Residues | 15 |
| Details | NEUROTR_ION_CHANNEL Neurotransmitter-gated ion-channels signature. CeIiVthFPfDeqnC |
| Chain | Residue | Details |
| B | CYS128-CYS142 |
| site_id | PS00272 |
| Number of Residues | 21 |
| Details | SNAKE_TOXIN Snake toxins signature. GCaatCPskkpyeevt.CCstD |
| Chain | Residue | Details |
| A | GLY43-ASP63 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEVVH |
| Chain | Residue | Details |
| C | TYR191-HIS197 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN141 |
