5H5S
Crystal structure of human GPX4 in complex with GXpep-3
Summary for 5H5S
Entry DOI | 10.2210/pdb5h5s/pdb |
Related | 5H5Q 5H5R |
Descriptor | Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, GXpep-3, GLYCEROL, ... (4 entities in total) |
Functional Keywords | phospholipid hydroperoxide glutathione peroxidase 4, selenocysteine, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 21057.05 |
Authors | Sogabe, S.,Kadotani, A.,Lane, W.,Snell, G. (deposition date: 2016-11-09, release date: 2016-12-07, Last modification date: 2023-11-08) |
Primary citation | Sakamoto, K.,Sogabe, S.,Kamada, Y.,Matsumoto, S.I.,Kadotani, A.,Sakamoto, J.I.,Tani, A. Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis Biochem. Biophys. Res. Commun., 482:195-201, 2017 Cited by PubMed: 27836545DOI: 10.1016/j.bbrc.2016.11.035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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