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5H5R

Crystal structure of human GPX4 in complex with GXpep-2

Summary for 5H5R
Entry DOI10.2210/pdb5h5r/pdb
Related5H5Q 5H5S
DescriptorPhospholipid hydroperoxide glutathione peroxidase, mitochondrial, GXpep-2, GLYCEROL, ... (4 entities in total)
Functional Keywordsphospholipid hydroperoxide glutathione peroxidase 4, selenocysteine, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight21241.19
Authors
Sogabe, S.,Kadotani, A.,Lane, W.,Snell, G. (deposition date: 2016-11-09, release date: 2016-12-07, Last modification date: 2023-11-15)
Primary citationSakamoto, K.,Sogabe, S.,Kamada, Y.,Matsumoto, S.I.,Kadotani, A.,Sakamoto, J.I.,Tani, A.
Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482:195-201, 2017
Cited by
PubMed: 27836545
DOI: 10.1016/j.bbrc.2016.11.035
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

218500

건을2024-04-17부터공개중

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