5H5R
Crystal structure of human GPX4 in complex with GXpep-2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | polymer | 169 | 19419.1 | 1 | UniProt (P36969) Pfam (PF00255) In PDB | Homo sapiens (Human) | PHGPx,Glutathione peroxidase 4,GSHPx-4 |
2 | B | GXpep-2 | polymer | 15 | 1730.0 | 1 | Enterobacteria phage T7 | ||
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A: 29 - 197 (UniProt: P36969)
PDB | External Database | Details |
---|---|---|
Ser 29 | Cys 29 | engineered mutation |
Ala 37 | Cys 37 | engineered mutation |
Ser 64 | Cys 64 | engineered mutation |
Ocs 73 | Sec 73 | engineered mutation |
Arg 93 | Cys 93 | engineered mutation |
Ser 102 | Cys 102 | engineered mutation |
Glu 134 | Cys 134 | engineered mutation |
Val 175 | Cys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 21149.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 21241.2 |