5FR2
Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178
Summary for 5FR2
Entry DOI | 10.2210/pdb5fr2/pdb |
Related | 5FR1 |
Descriptor | TRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, FARNESYL, ... (7 entities in total) |
Functional Keywords | signaling protein, lysine-acetylation, rhoa, ras-superfamily, rhogdi, cytoskeleton, gdp |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 47461.04 |
Authors | Kuhlmann, N.,Wroblowski, S.,Knyphausen, P.,de Boor, S.,Brenig, J.,Zienert, A.Y.,Meyer-Teschendorf, K.,Praefcke, G.J.K.,Nolte, H.,Krueger, M.,Schacherl, M.,Baumann, U.,James, L.C.,Chin, J.W.,Lammers, M. (deposition date: 2015-12-15, release date: 2016-01-13, Last modification date: 2024-01-10) |
Primary citation | Kuhlmann, N.,Wroblowski, S.,Knyphausen, P.,De Boor, S.,Brenig, J.,Zienert, A.Y.,Meyer-Teschendorf, K.,Praefcke, G.J.K.,Nolte, H.,Kruger, M.,Schacherl, M.,Baumann, U.,James, L.C.,Chin, J.W.,Lammers, M. Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation. J.Biol.Chem., 291:5484-, 2016 Cited by PubMed: 26719334DOI: 10.1074/JBC.M115.707091 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.35 Å) |
Structure validation
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