5FG4

Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe

Summary for 5FG4

• Entry DOI: 10.2210/pdb5fg4/pdb
• Descriptor: Peregrin, 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide (3 entities in total)
• Functional Keywords: peregrin, moz-morf complex, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P55201
• Total number of polymer chains: 1
• Total formula weight: 14144.01

Authors

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (deposition date: 2015-12-20, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)