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5FG4

Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APeregrinpolymer11613703.71UniProt (P55201)
Pfam (PF00439)
In PDB
Homo sapiens (Human)Bromodomain and PHD finger-containing protein 1,Protein Br140
2A4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamidenon-polymer440.31Chemie (5XE)
3waterwater18.073Chemie (HOH)
Sequence modifications
A: 626 - 740 (UniProt: P55201)
PDBExternal DatabaseDetails
Ser 625-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13703.7
Non-Polymers*Number of molecules1
Total formula weight440.3
All*Total formula weight14144.0
*Water molecules are not included.

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PDB entries from 2024-04-17

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