5F98
Crystal structure of RIG-I in complex with Cap-0 RNA
Summary for 5F98
Entry DOI | 10.2210/pdb5f98/pdb |
Related | 3TMI 5F9F 5F9H |
Descriptor | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ... (5 entities in total) |
Functional Keywords | complex, rig-i, capped rna, self versus non-self, innate immunity, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: O95786 |
Total number of polymer chains | 12 |
Total formula weight | 526753.45 |
Authors | Wang, C.,Marcotrigiano, J.,Miller, M.,Jiang, F. (deposition date: 2015-12-09, release date: 2016-01-13, Last modification date: 2024-03-06) |
Primary citation | Devarkar, S.C.,Wang, C.,Miller, M.T.,Ramanathan, A.,Jiang, F.,Khan, A.G.,Patel, S.S.,Marcotrigiano, J. Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc.Natl.Acad.Sci.USA, 113:596-601, 2016 Cited by PubMed: 26733676DOI: 10.1073/pnas.1515152113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.28 Å) |
Structure validation
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