5F98
Crystal structure of RIG-I in complex with Cap-0 RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... | Probable ATP-dependent RNA helicase DDX58 | polymer | 695 | 79594.7 | 6 | UniProt (O95786) Pfam (PF00270) Pfam (PF18119) Pfam (PF00271) Pfam (PF11648) In PDB | Homo sapiens (Human) | DEAD box protein 58,RIG-I-like receptor 1,RLR-1,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I |
| 2 | B, D, F, H, J... | RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3') | polymer | 24 | 7649.6 | 6 | synthetic construct | ||
| 3 | K, A, C, E, G... | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | K, A, C, E, G... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 5 | J, L, B, D, F... | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 458.2 | 6 | Chemie (M7G) |
Sequence modifications
A, C, E, G, I, K: 232 - 925 (UniProt: O95786)
| PDB | External Database | Details |
|---|---|---|
| Ser 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 523465.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3287.7 | |
| All* | Total formula weight | 526753.5 |
